Ozempic vs Rybelsus for Diabetes: One Is Injected While the Other Is a Pill

Rybelsus and Ozempic are both FDA-approved to help manage blood sugar in adults with type 2 diabetes. The American Diabetes Association (ADA) guidelines recommend using the medications in combination with diet and exercise. Rybelsus is a glucagon-like peptide-1 (GLP-1) receptor agonist.

• As with most drugs, some people can have an allergic reaction after taking Rybelsus.
• By stimulating insulin release from pancreatic beta cells in response to elevated blood sugar levels, Rybelsus aids in lowering blood glucose levels.
• The two drugs are similar in terms of A1C decrease and weight loss.
• However, both Rybelsus and Ozempic have been found effective for helping improve blood sugar levels in people with type 2 diabetes when used with diet and exercise.

It’s possible to take Rybelsus even if you don’t have diabetes. But, its intended use is to manage blood sugar levels in people with type 2 diabetes, and it’s only been FDA-approved for this purpose. Rybelsus is only FDA-approved for people with type 2 diabetes, though the medication is sometimes prescribed off-label for weight loss. It’s ultimately up to a qualified healthcare professional to determine whether Rybelsus is right for you.

Read this next

Other less common digestive side effects such as gas, acid reflux, and burping were also reported in clinical trials. A substantial minority of Ozempic where to buy rybelsus usersexperience gastrointestinal side effects. For some, the nausea, vomiting, or diarrhea subsides as their bodies acclimate to the powerful drug.

Weight loss can be a side effect of Rybelsus treatment for type 2 diabetes (see “Rybelsus side effects” above for details). If you have questions about Rybelsus and weight management, talk with your doctor. The SUSTAIN 2 trial assessed Ozempic in a similar population, people with type 2 diabetes using either metformin or a TZD. The 0.5mg dose of Ozempic conferred an A1C drop of 1.3 percentage points and a weight loss of 9.5 pounds.

Will I have hair loss with Rybelsus?

Both Rybelsus and Ozempic are manufactured by the drug company Novo Nordisk, says Dr. Comite. Their main differences are the route of administration, frequency and strength. In addition to boxed warnings, Rybelsus and Ozempic have other warnings. Rybelsus is an antidiabetic medication manufactured by Novo Nordisk, a global pharmaceutical company specializing in diabetes care. If you have questions about Rybelsus or insulin, talk with your doctor. If you have any questions about the timing of your Rybelsus doses and meals, talk with your doctor.

• The insurance company will review the request and let you and your doctor know if your plan will cover Rybelsus.
• Your doctor or pharmacist can tell you more about the potential side effects of Rybelsus.
• It’s used with a balanced diet and exercise to help manage blood sugar levels.
• For more information about how Rybelsus is used, see the “Is Rybelsus used for type 2 diabetes?
• However, before starting Rybelsus, ask your doctor or pharmacist if it’s safe for you to drink alcohol.

However, if you think you’re having a medical emergency, you should call 911 or your local emergency number. Your doctor or pharmacist can tell you more about the potential side effects of Rybelsus. Call your doctor at once if you have signs of a thyroid tumor, such as swelling or a lump in your neck, trouble swallowing, a hoarse voice, or shortness of breath.